Research Paper
Effect of Simultaneous Vitamin C & B6 Supplementation on Biochemical Values in Type 2 Diabetes- Mellitus
Author: Hossein Mirmiranpour 1, Alireza Esteghamati2*, Maryam Ebadi2, Shahnaz Khaghani3, Siavash Gerayesh- Nejad3, Mohammad Hossein Dehghan
1.Department of Biochemistry, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran
2. Endocrinology and Metabolism Research Center (EMRC), Vali-Asr Hospital, School of Medicine ,Tehran University of Medical Sciences, Tehran, Iran
3. Department of Biochemistry, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
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Abstract
Aims:
In this study, we aimed to evaluate the impact of long-term administration of a combination of vitamins B6 and C on the outcome of glycemic control on patients with T2DM.
Methods:
A total of 150 patients with T2DM were studied and randomly assigned to 2 groups. Both groups received Metformin and Atorvastatin; the experimental group was supplemented with a combination of vitamin C and B6 for a 6 months trial.
Results:
In the experimental group, systolic blood pressure showed a significant decrease.All laboratory measures improved significantly in the experimental group.
Conclusion:
A combination of vitamin C & B6 therapy inT2DM can lead to a decline in further complications resulting from increased biochemical values. and may pave the road to a beneficial therapeutic modality.
Keywords:
Diabetes Mellitus; Vitamin C; Vitamin B6; Supplementation
